Manzanillo is a city as well as its surrounding municipality in the Mexican state of Colima. The city, located on the Pacific Ocean, contains Mexico's busiest port.
In the 2005 census the city of Manzanillo had a population of 110,728 and its municipality had 137,842. It is the second-largest community in the state, after Colima, the capital. The municipality covers an area of 1,578.4 km² (609.42 sq mi), and includes such outlying communities as El Colomo, in addition to many smaller communities. Manzanillo is also a beach resort and, as the self-proclaimed "sailfish capital" of the world, hosts a yearly sailfish fishing tournament. The Revillagigedo Islands, off the west coast of Mexico in the Pacific Ocean, are part of the municipality.
Manzanillo is a sister city of the U.S. cities of Flagstaff, Arizona; San Pablo, California; and Saint Paul, Minnesota.